Hong Kong Dermatology & Venereology Bulletin

Volume 12 Number 1, Spring 2004

A lady with recurrent itchy papules: eczematid-like purpura of Doucas and Kapetanakis

PT Chan 陳寶德, WYM Tang 鄧旭明, WY Lam 林永賢

A 30-year-old lady with recurrent pruritic non-blanchable erythematous papules over the extremities was presented. Skin biopsy confirmed the clinical impression of eczematid-like purpura of Doucas and Kapetanakis. Her skin lesions ran a recurrent course despite oral antihistamines and topical steroids. Phototherapy only produced transient improvement. Topical tacrolimus was given as a therapeutic trial resulted in good control. To the authors' knowledge, this was the first report of the use of topical tacrolimus in the management of pigmented purpuric dermatitis. (H.K. Dermatol. Venereol. Bull. (2004) 12, 24-27)

病例為30 歲女性患者,四肢反復出現痕癢性紅色丘疹,壓診不褪色。皮膚組織活檢確診為道-凱 二氏濕疹樣紫癜。皮損反復發作,口服抗組胺藥及局部激素無效。光照治療僅令病情短暫舒緩。隨 後試用局部他克莫司,經兩個月治療後,皮損受到有效控制。就筆者所知,此為首例應用他克莫司 治療的色素性紫癜性皮膚病。

Keywords : Eczematid-like purpura of Doucas and Kapetanakis, tacrolimus


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