Hong Kong Dermatology & Venereology Bulletin

Volume 11 Number 1, Spring 2003

Paget's Disease of the Nipple

SY Cheng 鄭秀儀

This is a report of a 45-year-old Chinese woman who presented with an eight-month history of unilateral eczematous like rash on her left nipple-areola area. No breast mass was palpable. The skin biopsy confirmed the lesion to be Paget's disease of the nipple. Mammogram showed abnormal microcalcifications at the superio-lateral quadrant of the left breast. A left mastectomy was done and the histopathology of the mastectomy specimen confirmed an underlying high grade ductal carcinoma in-situ. (H.K. Dermatol. Venereol. Bull. (2003) 11, 26-29)

此病例之患者是位45歲女性,有八個月的左乳頭濕疹樣皮疹病史。觸診無乳房腫塊。皮膚活檢證實皮疹為乳頭乳暈炎性癌變 (Paget's disease)。病人隨後接受乳腺癌的有關檢查。乳腺軟性X光檢查顯示左側乳房外上部有異常微小鈣化。最後,施行左側乳房切除術,組織病理標本檢查證實病者患有乳腺管高度分化原位癌。

Keywords : Nipple, Paget's disease


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