Hong Kong Dermatology & Venereology Bulletin

Volume 10 Number 3, September 2002

Mycosis Fungoides: Facts and Controversies

Dr. L. S. Ku
Social Hygiene Service (Dermatology), Department of Health, Hong Kong

Mycosis fungoides (MF) is the commonest primary cutaneous T-cell lymphoma. The diagnosis of MF is basically by clinico-pathological correlation with the assistance of ancillary tools like gene rearrangement studies and immunophenotyping studies. There are no histological features that are pathognomonic of MF and inter- and intra-observer variations were well documented. Proper clinical staging using the TNM system is essential in its management. PUVA is a common treatment modality for MF and adequate maintenance PUVA therapy is important to keep the patient free from relapse. Combination therapy, either concomitant or sequential is the logical approach and biological response modifiers are likely to play an important role in the treatment of MF in the future.

Keywords : Cutaneous T-cell lymphoma, Mycosis fungoides, Sezary syndrome

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