Hong Kong Journal of Paediatrics

Volume 7 Number 4, October 2002
Abstract

Spastic Diplegia as a Complication of Interferon Alpha Treatment of Kasabach-Merritt Syndrome

NC SIN, CK LI , MK SHING, KW CHIK, PMP YUEN

Treatment of life threatening and yet steroid non-responsive Kasabath-Merritt syndrome patient with interferon alpha during infancy is associated with potentially irreversible spastic diplegia. Physicians should balance the risk and benefit of interferon treatment. Repeated clinical assessment of neuro-developmental status is mandatory in those interferon treated infants. Early discontinuation of interferon alpha treatment has the potential of reversal of early onset spastic diplegia. (HK J Paediatr (new series) 2002;7:220-222)

Key words : Interferon alpha; Kasabach-Merritt Syndrome; Spastic diplegia



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