Hong Kong Journal of Nephrology

Volume 6 Number 2, 2004
Abstract

Effect of Changing Transfer Set on Relapse of Bacterial Peritonitis

Flora Sau-Yung Wong
floraahnh@sinaman.com

Suet-Kwan Chau
Ngar-Yee Chow
Janita Chui-Fung Ho
Yuk-Lun Cheng
Alex Wai-Yin Yu

Renal Unit, Alice Ho Miu Ling Nethersole Hospital, New Territories, Hong Kong SAR, China.

Objective: To determine whether changing the transfer set on completion of antibiotic treatment for peritonitis affects the rate of relapsing peritonitis.
Methods: This randomized prospective study conducted in a renal unit in Hong Kong recruited all continuous ambulatory peritoneal dialysis (CAPD) patients who developed peritonitis and were successfully treated between August 2001 and October 2002. Exclusion criteria were tuberculosis or fungal peritonitis, relapsing peritonitis, peritonitis coexisting with exit-site or tunnel infection, and antibiotics due to infection of other origin. Patients were randomized to either transfer set change (Group I) or no transfer set change (Group II) on completion of antibiotic treatment.
Results: A total of 38 patients were recruited in Group I and 33 patients in Group II. The two groups were comparable for demographic data, duration of CAPD, and culture results. There were two episodes of relapsing peritonitis in both groups. There was no significant difference in relapsing peritonitis rates between patients who had the transfer set changed and those who did not have the transfer set changed.
Conclusions: Changing the transfer set on completion of antibiotic treatment for peritonitis does not reduce the relapsing peritonitis rate. This practice of transfer set change after antibiotic treatment may not be necessary to prevent relapsing peritonitis.

Key words: continuous ambulatory peritoneal dialysis, relapsing peritonitis, transfer set

目的:本研究的目的是為確定在腹膜炎治癒後更換中間喉會否影響受同一細菌引致的復發性腹膜炎的發生率。
方法:研究在一所透析中心進行,為一前瞻性隨機研究。研究的對像是所有在二零零一年八月至二零零二年十月間患腹膜炎而治癒的透析病人,有下列情況的病人除外:結核或黴菌腹膜炎;同一細菌引致的復發性腹膜炎;同時患有導管口或遂道感染及因其他感染而正在服用抗生素的病人。所有參與研究的病人會以抽籤方法分配於第一組或第二組內。第一組的參與者會在腹膜炎治癒後接受更換中間喉程序而第二組的參與者的中間喉則不會被更換。
結果:分別有三十八及三十三位參與者分配於第一組及第二組內。兩組參與者的特徵包括:年齡、性別、接受透析治療時間、患有糖尿病的人數及腹膜炎感染的菌種沒有顯著分別。結果顯示兩組參與者的受同一細菌引致的復發性腹膜炎的發生率沒有顯著的差異。
結論:在腹膜炎治癒後更換中間喉沒有減低受同一細菌引致的復發性腹膜炎的發生率。對於預防受同一細菌引致的復發性腹膜炎,更換中間喉被認為是沒有必要性的。


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