Hong Kong Journal of Nephrology

Volume 6 Number 1, 2004

Continuous Ambulatory Peritoneal Dialysis in a Patient with Human Immunodeficiency Virus Infection

Kim-Ming Wong, Yiu-Han Chan, Wai-Leung Chak, Man-Po Lee, Koon-Shing Choi, Ka-Foon Chau, Patrick Chung-Ki Li, Chun-Sang Li

We report the case of a female patient with human immunodeficiency virus (HIV) receiving highly active antiretroviral therapy (HAART) who developed end-stage renal failure requiring continuous ambulatory peritoneal dialysis (CAPD). She experienced polymicrobial CAPD-associated peritonitis and died about 1 month after initiation of CAPD. Although CAPD is an effective dialytic therapy, infection remains its Achilles' heel. The potential risk of HIV transmission by peritoneal dialysis effluent should be noted. HAART dose should be adjusted according to renal function to minimize adverse drug effects.

Key words: continuous ambulatory peritoneal dialysis, CAPD, end-stage renal failure, HIV

本個案報告為一位感染人類免疫缺乏病毒(HIV)的女性病人,於高活性抗反轉錄病毒治療(HAART)期間發生末期腎衰竭,並接受連續可活動性腹膜透析(CAPD)。在 CAPD 開始後 1 個月,她死於因 CAPD 併發之感染性腹膜炎。即使 CAPD 屬於行之有效的透析療法,但卻有導致感染性疾病之虞。此外,腹膜透析亦可能透過排放液造成 HIV 之傳播。在進行 HAART 期間,應密切注意劑量的調整,以降低不良作用對病人的影響。

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