Hong Kong Journal of Nephrology

Volume 6 Number 1, 2004

Short Daily and Long-hours Daily Nocturnal Hemodialysis: Methods, Outcomes and Future Directions

Gihad E. Nesrallah, Andreas Pierratos

Daily, or quotidian, hemodialysis continues to garner interest worldwide. The two most common forms in use are short daily hemodialysis (hemeral hemodialysis) and daily nocturnal hemodialysis. The currently accepted thrice-weekly dialysis regimen adopted some four decades ago was not designed to provide optimal patient outcomes, but rather to achieve some kind of compromise between adequacy, patient acceptance and economic factors. In the last decade, a number of observational studies have unanimously demonstrated multiple clinical benefits with more frequent dialysis. This paper reviews some important methodologic aspects of quotidian dialysis delivery and the outcomes literature in this field, including economics.

Key words: quotidian, nocturnal, hemeral, daily, hemodialysis, review

一天一次之血液透析(quotidian hemodialysis)可於晝間(hemeral)或夜間(nocturnal)施行,雖然並非目前主流的血液透析法,但在醫學界中仍持續引起廣泛的與趣。至於目前獲得廣泛應用的一天三次透析,已具有 40 多年的歷史,其目的並非為病人提供最佳的透析效果,而是在透析足夠度、病人接受度、及成本之間取得較佳的平衡。在過去 10 年間,多項觀察性研究已一致證實較頻繁的透析,可為病人提供多方面的臨床效益。本文對一天一次血液透析之施行方式、及實際表現(包括在經濟學上),作出了文獻的回顧。

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