Hong Kong Journal of Nephrology

Volume 5 Number 2, 2003
Abstract

Peritoneal Transport: From Basics to Bedside

Tao Wang, Bengt Lindholm

Comprehensive understanding of peritoneal solute and fluid transport is of clinical significance to nephrologists in guiding prescription of peritoneal dialysis. In this review, we discuss the basic knowledge of peritoneal transport and its relationship with the prescription of peritoneal dialysis and new peritoneal dialysis solutions. The roles of neoangiogenesis, peritoneal inflammation and changes in peritoneal hydraulic permeability, especially changes in tissue hyaluronan content and peritoneal surface layer, are also discussed. [Hong Kong J Nephrol 2003;5(2):65-72]

Key words: peritoneal transport, membrane permeability, kinetics, neoangiogenesis, peritoneal surface layer

對腹膜透析溶質轉運及水的轉運的充分理解,對臨床透析處方的制定有很大意義。本文綜述了腹膜轉運的基本知識以及它與腹膜透析處方及腹膜透析液的關係,也討論了新生血管增生、炎症及腹膜組織水通透性改變,特別是腹膜組織中透明質酸含量的改變以及腹膜表面層改變的意義。


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