Kai-Ming CHOW, Wai-Shan WONG, Viola Chi-Ying CHOW, Teresa Yuk-Hwa WONG, Natalie Pui-Ha CHAN, Philip Kam-Tao LI
Objective: Mycobacterium tuberculosis is an intracellular pathogen susceptible to macrophage action, which also has an important role in peritoneal defense. To explore the peritoneal host defense mechanism and inflammatory process, we longitudinally followed up 16 cases of continuous ambulatory peritoneal dialysis complicated by tuberculous peritonitis over the past 9 years in Prince of Wales Hospital.
Methods: Serial peritoneal fluid cell population was monitored in 16 end-stage renal disease patients with tuberculous peritonitis.
Results: The mean age of the participants was 53
Conclusion: Data in this study support the hypothesis that macrophages represent an important defense mechanism of the peritoneal cavity against mycobacterial infection and possibly the major peritoneal inflammatory process. (Hong Kong J Nephrol 2002;4(2):90-94)
Key words: Leukocytes, Macrophage activation, Mycobacterium tuberculosis, Peritoneal dialysis/continuous ambulatory, Phagocytosis
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