Journal of the Hong Kong Geriatrics Society

Volume 11 Number 1, January 2002

Clinical features of Alzheimer's disease in a Regional Memory Clinic in Hong Kong

KC Chiu, LW Chu, CP Chung, W Hu, F Chan, C Pei, SL Hui

Symptomatology of Alzheimer's Disease (AD) had been widely reported in Caucasian populations. Local data was lacking in Hong Kong. The aim of the present study was to review the clinical features of Alzheimer's disease in a regional Memory Clinic in Queen Mary Hospital. This was a retrospective case series analysis. Case records of patients attending the Queen Mary Hospital's Memory Clinic from 1/1/1997 to 30/6/2000 were reviewed. All patients who had probable AD (i.e. AD) by NINCDS-ADRDA criteria were recruited. Demographic data, presenting symptom, cognitive and non-cognitive symptoms, cognitive assessment scores, functional status and place of residence were documented and analyzed. Results: 96 AD patients were recruited. 72.9% were female. The mean age at first visit was 77.3 years (s.d.= 6.55 years). The interval between symptom onset and first visit was 3.1 years (s.d.=2.0 years). 90.6% presented to the clinic because of poor short-term memory. 83.3% had non-cognitive symptoms at clinical presentation. These included behavi oural changes ( 59. 4%) , perceptual / psychotic changes (51.0%), sleep (27.1%) and mood (24.0%) changes. In conclusions, the clinical features of AD among Chinese elderly patients in a regional Memory Clinic in Hong Kong shared many common features to those reported by Caucasian studies. There was a delay in symptom onset and in the proper assessment at the Memory Clinic (J HK Geriatr Soc 2002; 11:20-25)

Keywords : Alzheimer's Disease, Clinical features

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