External Beam Radiotherapy for Hürthle Cell Carcinoma of the Thyroid
JG Brabham, CG Morris, RJ Amdur, WM Mendenhall
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida, USA
Objective: To analyse the efficacy of external beam radiotherapy in patients with Hürthle cell carcinoma of the thyroid treated with curative intent.
Patients and Methods: Five patients received postoperative radiotherapy for suspected subclinical (3 patients) or gross residual (2 patients) disease after surgery. Patients were followed up from 15 to 72 months (median, 33 months).
Results: All the cancers were locally controlled. At last follow-up, 1 patient was alive and disease-free, 3 patients were alive with distant metastases, and 1 patient had died of intercurrent disease. No patient experienced a severe complication.
Conclusions: Hürthle cell carcinomas of the thyroid are likely to be radiosensitive, and external beam radiotherapy should be considered for patients with likely subclinical or gross residual disease after surgery.
Key Words: Hürthle cell carcinoma; Radiotherapy; Thyroid; Treatment outcomes
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