Journal of Hong Kong College of Radiologists

Volume 6 Number 1, 2003

Juvenile Nasopharyngeal Angiofibroma

WM Mendenhall,1 JW Werning,2 RW Hinerman,1 RJ Amdur,1 DB Villaret2
1Department of Radiation Oncology and 2Department of Otolaryngology, University of Florida College of Medicine, Gainesville, Florida

Review of the literature was performed to define the optimal treatment of patients with juvenile nasopharyngeal angiofibroma. Patients with extracranial juvenile nasopharyngeal angiofibroma have a high likelihood of cure with acceptable morbidity after surgery alone. Transnasal endoscopic resection is highly successful for selected patients. Patients with intracranial extension, as well as patients with juvenile nasopharyngeal angiofibroma that recurs after prior resection, may be treated with either surgery or radiotherapy depending on the likelihood of achieving a complete resection with acceptable morbidity. The chance of cure after moderate dose radiotherapy is approximately 85%. (J HK Coll Radiol 2003;6:15-19)

Key Words: Angiofibroma, Pharyngeal neoplasms, Radiotherapy, Vascular neoplasms

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