Journal of Hong Kong College of Radiologists

Volume 5 Number 3, 2002

Imaging Features of Crohn's Disease in Chinese People: A Preliminary Study

ASC Ching,1 HKF Mak,2 CKC Lai,3 CB Ip,1 HS Cheung1
1Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, 2Department of Diagnostic Radiology, Yan Chai Hospital, 3Department of Anatomical & Cellular Pathology, Prince of Wales Hospital, Hong Kong

Objective: A retrospective study to describe the imaging findings of Crohn's disease in Hong Kong Chinese patients. Patients and Methods: Radiological and cross-sectional imaging studies performed in a 3-year period (1997 to 2000) on 17 patients with proven Crohn's disease were reviewed. The findings were categorised as mild, moderate, and severe by radiological grading and a novel Combined Imaging Predictive Index. Results: Eleven patients (64.7%) had multifocal disease and 6 patients (35.3%) had focal disease. The terminal ileum was the most common site of involvement (70.6%). The most frequent findings were eccentric luminal change (52.9%) and thickened folds with nodularity (47.1%). By Combined Imaging Predictive Index, 11/17 patients (64.7%) had severe disease, 4/17 (23.5%) had intermediate disease, and 2/17 (11.8%) had mild disease. By radiological grading, 9/13 patients (69.2%) had severe disease, 4/13 (30.8%) had moderate disease, and none had mild disease. Conclusions: Crohn's disease in Chinese patients frequently involves the terminal ileum and exhibits eccentric luminal change and nodular thickened folds. The radiological features do not appear to be substantially different from those described in the West. Combined Imaging Predictive Index may be useful in describing Crohn's disease, but further prospective study is required to confirm its clinical value. (J HK Coll Radiol 2002;5:162-169)

Key Words: Chinese, Crohn's disease, Diagnostic imaging, Inflammatory bowel diseases

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