Journal of Hong Kong College of Radiologists

Volume 4 Number 1, 2001

Inherited Susceptibility to Breast Cancer

US Khoo
Department of Pathology, The University of Hong Kong, Hong Kong

The significance of BRCA1, and BRCA2 genes in the carcinogenesis of breast cancer has been discussed. The potential role of hormonal preventive treatment and prophylactic mastectomy and oophorectomy in carriers of the mutant genes has been debated. A careful surveillance for both breast cancer and ovarian cancer is indicated in carriers of the genes. (J HK Coll Radiol 2001;1:41-43)

Key words : BRCA1, BRCA2, Genes, Breast cancer

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