Fractional Flow Reserve: Overview and Implications for Clinical Decision Making

William Kong-to Hau
From Department of Physiology and Institute of Cardiovascular Science and Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong

HAU: Fractional Flow Reserve: Overview and Implications for Clinical Decision Making. Pressure derived fractional flow reserve (FFR) is a well-validated index to assess functional significance of stenosis severity that has evolved from a physiological index to a clinical tool. The objective of this paper is to provide a short overview of the theoretical and physiological background of this physiological assessment technique and to focus on its clinical applicability in both diagnostic and interventional procedures. (J HK Coll Cardiol 2003;11:83-89)

Key words : Fractional flow reserve, hyperemia, pressure guide wire, vasodilator

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