| Abstract |
Vedran Kovacic,1 Luka
Roguljic,2 Vinko Kovacic,3
Boris Bacic,4 Tamara Bosnjak5
From 1Hemodialysis Department,
Medical Center Trogir, Trogir, Croatia; 2Urgent
Medicine Department, Medical Center Ploce, Ploce, Croatia; 3Special
Geriatric Hospital, Trogir, Croatia; 4The
Clinic of Obstetrics and Gynecology, Split University Hospital, Split, Croatia;
5Urgent Medicine Department, Split University
Hospital, Split, Croatia
Kovacic et al: Ultrafiltration Volume is Associated with Changes in Blood
Pressure in Chronically Hemodialyzed Patients. Introduction: Volume
overload is a main factor in development of hypertension in hemodialysis patients.
In order to demonstrate impact of ultrafiltration volume on blood pressure during
15-month period in a group of patients undergoing chronic hemodialysis therapy,
we conducted this study. We hypothezed that ultrafiltration volume different
affects the pre/postdialysis systolic pressure, diastolic pressure, mean arterial
pressure (MAP) and pulse pressure (PP) values. Subjects and Methods:
Study subjects were 23 anuric chronically hemodialyzed patients. The overall
study time was 15 months, and 136 single hemodialysis treatments were analyzed.
Results: Ultrafiltration was negatively correlated with predialysis systolic
blood pressure (r=-0.169, p=0.025), postdialysis systolic blood pressure (r=-0.292,
p<0.001), postdialysis MAP (r=-0.186, p=0.015), predialysis PP (r=-0.290,
p<0.001), and postdialysis PP (r=-0.370, p<0.001). Ultrafiltration/dry
body mass (UF/W) ratio was negatively correlated with predialysis PP (r=-0.222,
p=0.005), postdialysis PP (r=-0.340, p<0.001), and postdialysis systolic
blood pressure (r=-0.243, p=0.002). We found significant difference in postdialysis
PP between dialyses with UF/W ratio <= 0.05 and dialyses with UF/W ratio
>0.05 (63.49
Key words : Blood pressure, hemodialysis, ultrafiltration