Asian Journal of Nuclear Medicine
亞洲核醫學雜志

Volume 2 Number 1, March 2002
Abstract

雲克與153Sm-EDTMP聯合治療27例腫瘤轉移性骨痛療效觀察

邱陵,張春銀,陳躍,陳伯勳
四川瀘州醫學院附屬醫院核醫學科 瀘州 646000,中國

目的 瞭解雲克與153Sm-EDTMP聯合治療腫瘤轉移性骨痛的療效,以及是否優於單用153Sm-EDTMP治療的療效。方法 分兩組治療,一組用雲克與153Sm-EDTMP聯合治療;另一組單用153Sm-EDTMP。結果 聯合治療組:27例,骨痛完全緩解29.6%,骨痛部分緩解55.6%,止痛總有效率85.2%;無效14.8%。153Sm-EDTMP組40例,骨痛完全緩解22.5%,骨痛部分緩解42.5%,止痛總有效率65%,無效35%。結論 聯合療法治療重度骨痛和多發性骨轉移灶效果較好,優於單用153Sm-EDTMP。

【關鍵詞】99Tc-MDP; 153Sm-EDTMP; 腫瘤轉移性骨痛

The combined treatment effect of metastasis bone pain with Yunke and 153Sm-EDTMP

Qiu Ling, Zhang Chunyin, Chen Yue, Chen Boxun
Department of Nuclear Medicine, Hospital of Luzhou Medical College, Sichuan Province, Luzhou 646000, China.

Objective To investigate the effect of Yunke (99Tc-MDP) with 153Sm-EDTMP on metastasis bone pain and to compare with 153Sm-EDTMP. Methods 67 patients with metastasis bone pain were divided into Yunke with 153Sm-EDTMP group (27 cases), 153Sm-EDTMP group (40 cases). The effects were evaluated by total effective rate, using principal symptoms, body weight, and thyroid hormone after 6 months. Results The bone pain remissive completely and total effective and no effect rate were 29.6%, 85.2% and 14.8% in Yunke with 153Sm-EDTMP group. The bone pain remissive completely and total effective and no effect rate were 42.5%, 65%, and 35% in 153Sm-EDTMP group. Conclusion Compared with 153Sm-EDTMP, the combination of Yunke with 153Sm-EDTMP could enhance the therapeutic effect of metastasis bone pain.

Key Words: 99Tc-MDP; 153Sm-EDTMP; metastasis bone pain



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