Asian Journal of Nuclear Medicine
亞洲核醫學雜志

Volume 2 Number 1, March 2002
Abstract

β發射體的輻射效應研究及治療機理的物理學探討

陳志才,趙欣,郭紅源,吳猛,王燕伶,賈靜
中國原子能科學研究院,北京275信箱66分箱,北京102413,中國

目的 研究β發射體的輻射效應,探討β發射體的治療機理。方法 以90Sr/90Y前列腺增生治療器作為核輻射源,通過專門的實驗裝置,得到電子加光子的混合輻射和單純的光子輻射。在樣品位置,用LiF熱釋光片作吸收劑量測定;分別輻照有機液體和大腸桿菌懸濁液後,分別用紅外光譜技術和細菌顯微計數法,作輻射效應研究。結果 所有受專門輻照過的樣品,在紅外吸收譜上或大腸桿菌存活數上,與未受專門輻照的原始樣品有明顯差別。這說明,輻照效應是確實存在的。與單純受到光子輻射的樣品相比較,處於β粒子最大射程以外6mm處受電子加光子混合輻射輻照的樣品,受到的吸收劑量明顯小,但其輻照效應卻顯著大,這說明,在β粒子最大射程以外,β粒子的輻照效應仍然明顯存在,對此在物理學上可以有幾種解釋。結論 β發射體的輻射效應是β粒子及其次級輻射共同產生的結果,在β發射體的治療機理研究中,用核輻射與物質相互作用中能量轉移的波粒二重性假設是有意義的。

【關鍵詞】β發射體;輻射效應;治療機理;能量轉移;波粒二重性

Studies of radiation effects and physics exploration of therapy mechanism for b-emitter

Chen Zhicai, Zhao Xin, Guo Hongyuan, Wu Meng, Wang Yanling, Jia Jing
China Institute of Atomic Energy, P.O. Box 275 (66), Beijing 102413, P.R.China.

Objective 1. To study the radiation effects of b-emitter. 2. To explorer the therapy mechanism for b-emitter. Methods Using a 90Sr/90Y prostatic hyperplasia applicator as radiation source, adopting a special experiment equipment, two kinds of bunch of radiations, the mixture radiation of electrons and photons and singular photon radiation, were produced. The absorbed dose rate of sample positions was determined with LiF TLD's. Two kinds of liquid samples, the organic liquid and turbid liquid of colon bacilli, had been irradiated and then analysed by infrared molecule spectra or counts of living bacilli for research of radiation effects. Results Comparing with non-irradiated samples, all of the irradiated samples have shown significant difference in the infrared absorbed spectra or counts of living colon bacilli; the existence of radiation effects is authentic. While, as compared with the samples irradiated by the singular photon radiation, the sample, located at the position 6 mm beyond the maximum range of b-particles and irradiated by the mixture radiation, had lower absorbed dose, but it's radiation effects is larger. Such phenomenon implies that at the position 6mm beyond the maximum range of b-particles, the radiation effects from b-particles are still existed which may be explained in several aspects in physics. Conclusions The radiation effects of b-emitter had resulted from the action of b-particles and it's secondary radiation. In the research of therapy mechanism for b-emitter, applying the assumption of wave-particle duality of energy transfer in interaction between nuclear radiation and matter is meaningful.

Key Words : b-emitter; Radiation effects; Therapy mechanism; Energy transfer, Wave-particle duality



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